Methylmercury toxicity and functional programming☆
نویسندگان
چکیده
منابع مشابه
Dietary and tissue selenium in relation to methylmercury toxicity.
Selenium (Se) supplementation in the nutritionally relevant range counteracts methylmercury (MeHg) toxicity. Since Se tends to be abundant in fish, MeHg exposures alone may not provide an accurate index of risk from fish consumption. Molar ratios of MeHg:Se in the diets and Hg:Se in tissues of exposed individuals may provide a more accurate index. This experiment compared MeHg toxicity in relat...
متن کامل[Selenium deficiency and brain functions: the significance for methylmercury toxicity].
Selenium has been long recognized as one of the essential trace elements. Although many selenoproteins have been identified in the last decade, the physiological roles of Se and selenoproteins remain to be elucidated. Since iodothyronine deiodinases (DIs), which regulate the tissue levels of thyroid hormone, are (likely to be) selenoproteins, Se might have specific roles for developing brain. I...
متن کاملAn Uneven Path Forward: The History of Methylmercury Toxicity Research
Organic mercury compounds were first described in the 1800s, with fatal cases of methylmercury poisoning reported in 1865. Early reports described a distinct set of symptoms of methylmercury toxicity, including altered sensation in the face and extremities, tunnel vision, deafness , loss of coordination, and impaired speech. Nearly a century later, against a backdrop of widespread environmental...
متن کاملRecent evidence from epidemiological studies on methylmercury toxicity.
More than fifty years have passed since the outbreak of Minamata disease, and large-scale methylmercury poisoning due to industrial effluents or methylmercury-containing fungicide intoxication has scarcely happened in developed countries. On the other hand, widespread environmental mercury contamination has occurred in gold and mercury mining areas of developing countries. In this article, we p...
متن کاملEffects of Diphenyl Diselenide on Methylmercury Toxicity in Rats
This study investigates the efficacy of diphenyl diselenide [(PhSe)2] in attenuating methylmercury- (MeHg-)induced toxicity in rats. Adult rats were treated with MeHg [5 mg/kg/day, intragastrically (i.g.)] and/ or (PhSe)2 [1 mg/kg/day, intraperitoneally (i.p.)] for 21 days. Body weight gain and motor deficits were evaluated prior to treatment, on treatment days 11 and 21. In addition, hepatic a...
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ژورنال
عنوان ژورنال: Reproductive Toxicology
سال: 2007
ISSN: 0890-6238
DOI: 10.1016/j.reprotox.2007.03.002